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Publication List

2024年

  1. Near-room-temperature π-conjugated nematic liquid crystals in molecules with a flexible seven-membered ring structure, Iwai, R.; Yoshida, H.; Arakawa, Y.; Sasaki, S.; Iida, Y.; Igawa, K.; Sakurai, T.; Suzuki, S.; Tokita, M.; Watanabe, J.; Konishi, G. Aggregate, 2024; e660.

  2. Mammalian target of differentiation-inducing factor-1 is mitochondrial malate dehydrogenase for activation of AMP-activated protein kinase and induction of mitochondrial fission, Arioka, M.; Miura, K.; Han, R.; Igawa, K.; Takahashi-Yanaga, F.; Sasaguri, T. Life Sciences, 2024, 122807.

  3. Stereoselective Synthesis of Multi-functionalized Chiral Silacyclopentanes, Kuroo, A.; Igawa, K.; Tomooka, K. Chemistry Letters, 2024, 53, upae039.

  4. Linkage-Editing Pseudo-Glycans: A Reductive α‐Fluorovinyl‐C‐Glycosylation Strategy to Create Glycan Analogs with Altered Biological Activities, Moriyama, T.; Yoritate, M.; Kato, N.; Saika, A.; Kusuhara, W.; Ono, S.; Nagatake, T.; Koshino, H.; Kiya, N.; Moritsuka, N.; Tanabe, R.; Hidaka, Y.; Usui, K.; Chiba, S.; Kudo, N.; Nakahashi, R.; Igawa, K.; Matoba, H.; Tomooka, K.; Ishikawa, E.; Takahashi, S.; Kunisawa, J.; Yamasaki, S.; Hirai, G. Journal of The American Chemical Society, 2024, 146, 2237.

  5. Selenium-linked cyanobiphenyl-based liquid crystal dimers: the effects of chalcogen linkage and spacer length on the twist-bend nematic phase, Arakawa, Y.; Shiba, S.; Igawa, K. Liquid Crystals, 2024, 51, 1506.

  6. 2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induced myocardial infarction, Kishigami, T.; Ishikane, S.; Arioka, M.; Igawa, K.; Nishimura, Y.; Takahashi-Yanaga, F. Journal of Pharmacological Sciences, 2024, 154, 97.

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2023年

  1. Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells, M. Arioka, F. Seto-Tetsuo, T. Inoue, K. Miura, S. Ishikane, K. Igawa, K. Tomooka, F. Takahashi-Yanaga, T. Sasaguri, Life Science, 2023, 335, 122278.

  2. Development of DACN-NHS ester and DACN-maleimide, and their application for the synthesis of artificial hybrid biomolecules, Kawasaki, Y.; Hayashibara, T.; Seto, Y.; Taniguchi, Y.; Igawa, K.; Tomooka, K. Chemical Communication, 2023, 59, 11724.

  3. Phase behaviour of ester-linked cyanobiphenyl dimers and fluorinated analogues: the direct isotropic to twist-bend nematic phase transition, Arakawa, Y.; Horita, K.; Igawa, K., Liquid Crystals, 2023, accepted.

  4. Differentiation-inducing Factor 1 activates Cofilin through Pyridoxal Phosphatase and Amp-activated Protein Kinase, Resulting in Mitochondrial Fission, Inoue, T.; Miura, K.; Han, R.; Seto-Tetsuo, F.; Arioka, M.; Igawa, K.; Tomooka, K.; Sasaguri, T., Journal of Pharmacological Sciences, 2023, 152, 39-49.

  5. DIF-1 Exhibits Anticancer Activity in Breast Cancer via Inhibition of CXCLS/ CXCR2 Axis-mediated Communication between Cancer-associated Fibroblasts and Cancer Cells, Seto-Tetsuo, F.; Arioka, M.; Miura, K.; Inoue, T.; Igawa, K.; Tomooka, K.; Sasaguri, T., International Immunopharmacology, 2023, 117, 109913.
     

2022年

  1. Oxidation of an Internal-Edge-Substituted [5]Helicene-Derived Phosphine Synchronously Enhances Circularly Polarized Luminescence, Usui, K.; Narita, N.; Eto, R.; Suzuki, S.; Yokoo, A.; Yamamoto, K.; Igawa, K.; Iizuka, N.; Mimura, Y.; Umeno, T.; Matsumoto, S.; Hasegawa, M.; Tomooka, K.; Imai, Y.; Karasawa, S., Chemistry-A European Journal, 2022, 28, e202202922.

  2. 4 '-Alkylseleno-4-cyanobiphenyls, nSeCB: synthesis and substituent effects on the phase-transition and liquid crystalline behaviors, Arakawa, Y; Shiba, T; Igawa, K; Sasaki, S; Tsuji, H, CrystEngComm, 2022, 7592-7601.

  3. Flexible Alkylene Bridges as a Tool To Engineer Crystal Distyrylbenzene Structures Enabling Highly Fluorescent Monomeric Emission, Shimomura, Y; Igawa, K; Sasaki, S; Sakakibara, N; Goseki, R; Konishi, G, Chemistry-A European Journal, 2022, 28, e202201884.

  4. Synthesis, Stereochemical Analysis, and Transformation of Oxa-[7] orthocyclophene, Tomooka, K; Iso, C; Hashimoto, Y; Suzuki, M; Kawasaki, Y; Igawa, K, Chemistry Letters, 2022, 51, 7. 788-790.

  5. Synthesis and Stereochemical Analysis of Ten-membered Diallylic Nitrogen Cycle and Its Pt-Complex, Hayashi, J; Suzuki, M; Shimada, M; Kawasaki, Y; Igawa, K; Tomooka, K, Chemistry Letters, 2022. 51, 636-638.

  6. Stereochemical study on planar-chiral cyclic molecules using polysaccharide-based column chromatography, Igawa, K; Uehara, K; Kawasaki, Y; Tomooka, K, Chirality, 2022, 34, 824-832.

  7. Synthesis and Stereochemical Analysis of Planar Chiral Nine-Membered Aza-Orthocyclophyne, Kawasaki, Y; Tanaka, S; Igawa, K; Tomooka, K, Heterocycles, 2022, 105, 352-357.

  8. 2,5-Dimethylcelecoxib attenuates cardiac fibrosis caused by cryoinjury-induced myocardial infarction by suppressing the fibroblast-to-myofibroblast transformation via inhibition of the TGF-beta signaling pathway, Ikushima, E; Ishikane, S; Kishigami, T; Matsunaga, H; Igawa, K; Tomooka, K; Nishimura, Y; Takahashi-Yanaga, F, Biochemical Pharmacology, 2022, 197, 114950.

  9. Effects of Alkylthio Groups on Phase Transitions of Organic Molecules And Liquid Crystals: A Comparative Study With Alkyl And Alkoxy Groups, Arakawa, Y; Ishida, Y; Shiba, T; Igawa, K; Sasaki, S; Tsuji, H, CrystEngComm, 2022, 24, 1877-1890.

  10.  3-Azidoarynes: Generation and Regioselective Reactions, Taguchi, J; Kimura, K; Igawa, K; Tomooka, K; Hosoya, T, Chemistry Letters, 2022, 51, 94-98.

  11. Preparation of Enantioenriched Helical- and Axial-Chiral Molecules by Dynamic Asymmetric Induction, Kawasaki, Y; Kamikubo, R; Kumegawa, Y; Ogawa, K; Kashiwagi, T; Ano, Y; Igawa, K; Tomooka, K, Chemical Communications, 2022, 58, 1605-1608.

  12. Preparation of Oxysterols by C-H Oxidation of Dibromocholestane with Ru(Bpga) Catalyst, Fujii, Y; Yoritate, M; Makino, K; Igawa, K; Takeda, D; Doiuchi, D; Tomooka, K; Uchida, T; Hirai, G, Molecules, 2022, 27, 225.

 

2021年

  1. DIF-1 Inhibits Growth and Metastasis of Triple-Negative Breast Cancer Through Ampk-Mediated Inhibition of The Mtorc1-S6K Signaling Pathway, Seto-Tetsuo, F; Arioka, M; Miura, K; Inoue, T; Igawa, K; Tomooka, K; Takahashi-Yanaga, F; Sasaguri, T, Oncogene, 2021, 40, 5579-5589.

  2. Analysis of Stereochemical Stability of Dynamic Chiral Molecules Using an Automated Microflow Measurement System, Igawa, K; Asano, S; Yoshida, Y; Kawasaki, Y; Tomooka, K, Journal of Organic Chemistry, 2021, 86, 9651-9657.

  3. Cardiac and Renal Protective Effects Of 2,5-Dimethylcelecoxib in Angiotensin II and High-Salt-Induced Hypertension Model Mice, Yamamoto, M; Takahashi-Yanaga, F; Arioka, M; Igawa, K; Tomooka, K; Yamaura, K; Sasaguri, T, Journal of Hypertension, 2021, 39, 892-903.

  4. Carbonyl- and Thioether-Linked Cyanobiphenyl-Based Liquid Crystal Dimers Exhibiting Twist-Bend Nematic Phases, Arakawa, Y; Komatsu, K; Ishida, Y; Igawa, K; Tsuji, H, Tetrahedron, 2021, 81, 131870.

  5. Differentiation-Inducing Factor-1 Potentiates Adipogenic Differentiation and Attenuates The Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells, Ishikane, S; Ikushima, E; Igawa, K; Tomooka, K; Takahashi-Yanaga, F, Biochimica et Biophysica Acta-Molecular Cell Research, 2021, 1868, 118909.

 

​2020年

  1. Birefringence and Photoluminescence Properties of Diphenylacetylene-Based Liquid Crystal Dimers, Arakawa, Y; Sasaki, S; Igawa, K; Tokita, M; Konishi, G; Tsuji, H, New Journal of Chemistry, 2020, 44, 17531-17541.

  2. (Hexafluoroacetylacetonato)Copper(I)-Cycloalkyne Complexes as Protected Cycloalkynes, Makio, N; Sakata, Y; Kuribara, T; Adachi, K; Hatakeyama, Y; Meguro, T; Igawa, K; Tomooka, K; Hosoya, T; Yoshida, S, Chemical Communications, 2020, 56, 11449-11452.

  3. Selective Strain-Promoted Azide-Alkyne Cycloadditions Through Transient Protection of Bicyclo[6.1.0]Nonynes with Silver or Gold, Adachi, K; Meguro, T; Sakata, Y; Igawa, K; Tomooka, K; Hosoya, T; Yoshida, S, Chemical Communications, 2020, 56, 9823-9826.

  4. Natural Dolapyrrolidone: Isolation and Absolute Stereochemistry of A Substructure of Bioactive Peptides, Murakami, A; Hayashi, JI; Igawa, K; Tsutsumi, M; Tomooka, K; Nagai, H; Nehira, T, 2020, Chirality, 32, 1152-1159.

  5. 1,2-Insertion Reactions of Alkynes Into Ge-C Bonds of Arylbromogermylene, Sugahara, T; Ferao, AE; Planells, AR; Guo, JD; Aoyama, S; Igawa, K; Tomooka, K; Sasamori, T; Hashizume, D; Nagase, S; Tokitoh, N, Dalton Transactions, 2020, 49, 7189-7196.

  6. Bridged Stilbenes: AIEgens Designed via a Simple Strategy to Control the Non-radiative Decay Pathway, Iwai, R; Suzuki, S; Sasaki, S; Sairi, AS; Igawa, K; Suenobu, T; Morokuma, K; Konishi, G, Angewandte Chemie International Edition, 2020, 59, 10566-10573.

  7. Ozone Oxidation of Silylalkene: Mechanistic Study and Application for the Synthesis of Silacarboxylic Acid Derivatives, Igawa, K; Kawasaki, Y; Nozaki, S; Kokan, N; Tomooka, K, 2020, 85, 4165-4171.

  8. Copper-Free Huisgen Cycloaddition for the 14-3-3-Templated Synthesis of Fusicoccin-Peptide Conjugates, Masuda, R; Kawasaki, Y; Igawa, K; Manabe, Y; Fujii, H; Kato, N; Tomooka, K; Ohkanda, J, Chemistry-An  Asian Journal, 2020, 15, 742-747.

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2020年よりも以前の論文はこちら（まだ，リスト作成途中です）．

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